By T. T. Hansel (Editor), Peter J. Barnes (Editor)
This e-book offers a cutting-edge account by way of educational breathing physicians and senior pharmaceutical body of workers at the improvement of latest medicinal drugs for bronchial asthma, allergic reaction and COPD. It includes eighty chapters of hugely condensed details, provided in an enticing, reader-friendly layout with a lot use of tables, figures and diagrams. as well as summarizing the various diversity of present methods, this guide additionally seems to be into the long run, contemplating many themes which are promising, yet have in simple terms emerged within the previous few years. advancements inside confirmed drug different types comparable to beta-2-agonists, steroids and leukotriene antagonists also are reviewed. by no means ahead of has a unmarried publication introduced jointly such a lot of pharmaceutical drug builders sharing their adventure on any such wide variety of respiration issues!
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Extra info for New Drugs for Asthma, Allergy and Copd (Progress in Respiratory Research)
Jeffery, DSc, PhD Lung Pathology Unit Royal Brompton Hospital Sydney Street, London SW3 6NP (UK) Tel. uk 29 Hansel TT, Barnes PJ (eds): New Drugs for Asthma, Allergy and COPD. Prog Respir Res. Basel, Karger, 2001, vol 31, pp 30–34 OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Monitoring Lung Function Neil Pride Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College School of Medicine, London, UK Summary Measurement of airway function is central to the diagnosis and assessment of asthma and COPD.
Recently, clinical development was initiated with rhDNase delivered by the AERx aqueous bolus delivery system with a view to shortening the delivery time and therefore enhancing compliance with the therapy . Soluble IL-4 Receptor. Nuvance (Immunex), an IL-4 receptor, administered by inhalation via a nebulizer, is currently being studied for the treatment of asthma . Anti-IgE Antibodies. While anti-IgE antibodies administered by injection showed efficacy in allergic asthmatic subjects , clinical trials with the inhaled product failed to demonstrate similar positive effects .
13 Smaldone GC, Agosti J, Castillo R, Cipolla D, Blanchard J: Deposition of radiolabeled protein from AERx in patients with asthma (abstract 38). J Aerosol Med 1999;12:98. 14 Mudumba S, Khossravi M, Yim D, Rossi T, Pearce D, Hughes M, Cipolla D, Sweeney T: Delivery of rhDNase by the AERx pulmonary delivery system; in Dalby RN, Byron PR, Farr SJ (eds): Respiratory Drug Delivery VI. Buffalo Grove, Interpharm Press, in press. 15 Cipolla D, Boyd B, Evans R, Warren S, Taylor G, Farr S: Bolus administration of INS-365: Studying the feasibility of delivering high doses of drug using the AERx pulmonary delivery system; in Dalby RN, Byron PR, Farr SJ (eds): Respiratory Drug Delivery VI.