Download Neuroscientific Foundations of Anesthesiology by George A. Mashour PDF

By George A. Mashour

Even if the perioperative care of sufferers by means of anesthesiologists attracts on different medical abilities, the rules of anesthesiology and soreness administration are rooted within the neurosciences. The Neuroscientific Foundations of Anesthesiology completely examines the anesthetic modulation of the critical, peripheral, and autonomic apprehensive platforms and should aid redefine anesthesiology as a essentially neuroscientific box. The ebook is geared up by means of sections, with every one concentrating on a unique a part of the anxious process. state of the art chapters written by way of thought-leaders in anesthesiology and neuroscience offer a singular and important source.

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Mol Pharmacol. 2001;59(4):814–824. 49. Nusser Z , Mody I. Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells. J Neurophysiol. 2002; 87(5):2624–2628. 50. Stell BM, Mody I. Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons. J Neurosci. 2002;22 RC223:1–5. 51. Belelli D, Peden DR , Rosahl TW, Wafford KA, Lambert JJ. Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics. J Neurosci.

Korpi ER , Grunder G, Luddens H. Drug interactions at GABA(A) receptors. Prog Neurobiol. 2002;67(2):113–159. 36. Franks NP. Molecular targets underlying general anaesthesia. Br J Pharmacol. Jan 2006;147 Suppl 1:S72–81. 37. Maconochie DJ, Zempel JM, Steinbach JH. How quickly can GABAA receptors open? Neuron. 1994;12(1):61–71. 38. Cobb SR , Buhl EH, Halasy K , Paulsen O, Somogyi P. Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature. 1995;378(6552):75–78.

HCN channels: structure, cellular regulation and physiological function. Cell Mol Life Sci. 2009;66(3):470–494. (2) Reprinted with permission from Chen X, Shu S, Kennedy DP, Willcox SC, Bayliss DA. Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice. J Neurophysiol. Jan 2009;101(1):129–140. (3) Reprinted with permission from Cacheaux LP, Topf N, Tibbs GR, et al. Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.

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