Download Drug Delivery to the Oral Cavity: Molecules to Market (Drugs by Tapash K. Ghosh, William R. Pfister PDF

By Tapash K. Ghosh, William R. Pfister

With contributions from famous experts in undefined, academia, and govt, this reference offers the cutting-edge within the checking out, formula, and medical review of intraoral drug supply products-summarizing intraoral dosage kinds in a variety of phases of study, in addition to items presently out there.

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Additional info for Drug Delivery to the Oral Cavity: Molecules to Market (Drugs and the Pharmaceutical Sciences)

Example text

DMSO: Dimethylsulfoxide. DOE: Design of experiments. Dp: Bottom plate diameter at pilot scale. DP: Diffusion coefficient in the intercellular spaces. DT: Diffusion coefficient in the lipophilic phase. DTC: Direct-to-consumer. EDTA: Ethylenediamine tetracetic acid. EM: Electron microscopic. Eu: Eudragit. fm copy Page 392 Saturday, January 8, 2005 9:47 PM 392 EVA: Ethylene vinyl acetate. FD: Fluorescein isothiocyanate labeled dextrans. FDA Food and Drug Administration (Agency). FIP: International Pharmaceutical Federation.

Rx: Prescription. s: Sample standard deviation. SCN: Suprachiasmatic nucleus. SD: Slow dissolving. SDST: Slow dissolving sublingual tablet. SP: Suitability petition. SPC: Statistical process capability.. SRP: Scaling and root planning. ST: Sublingual table. STDHF: Sodium taurodihydrofusidate. T1/2: Plasma half-life, or drug elimination half-life. TDD: Transdermal. TEER: Transepithelial electrical resistance. Tg: Glass transition temperature. TGF-: Transforming growth factor-. Tmax: Time to reach maximum plasma concentration.

K: Non-centering correction factor. KDa: KiloDaltons. KP: Partition coefficient between the lipophilic phase and the aqueous hydrophilic donor phase. LC/MS/MS: Liquid chromatography/mass spectroscopy/mass spectroscopy. LD50: Lethal dose resulting in 50 percent mortality. LHRH: Leutinizing hormone releasing hormone. LMDS: Liquid metered dose spray. LO: Lozenge. LOD: Loss on drying. LPC: Lysophosphatidylcholine. LSL: Lower specification limit. MAD: Mucoadhesive bioerodable pre-formed disc. MAO: Monoamine oxidase.

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