Download Devalued and Distrusted: Can the Pharmaceutical Industry by John L. LaMattina PDF

By John L. LaMattina

An expert's view on fixing the demanding situations confronting latest pharmaceutical industry

Author John LaMattina, a thirty-year veteran of the pharmaceutical and previous president of Pfizer's worldwide R&D department, is across the world well-known as knowledgeable at the pharmaceutical undefined. His first e-book, Drug Truths: Dispelling the Myths approximately Pharma R&D, used to be seriously acclaimed for clearing up misconceptions concerning the pharmaceutical and delivering a good account of the contributions of pharmaceutical study and improvement to human overall healthiness and well-being.

As he toured the rustic discussing Drug Truths, Dr. LaMattina on a regular basis came upon those that have been choked with anger, accusing the pharmaceutical of constructing up illnesses, hiding risky unintended effects, and extra. This e-book was once written according to that have, severely reading public perceptions and realities.

Starting with "4 secrets and techniques that Drug businesses don't desire You to Know," Devalued and Distrusted presents a fact-based account of ways the pharmaceutical works and the demanding situations it faces. It addresses such severe matters as:

  • Why pharmaceutical R&D productiveness has declined
  • Where pharmaceutical businesses have to make investments their resources
  • What should be performed to unravel center health and wellbeing demanding situations, together with melanoma, diabetes, and neurodegenerative diseases
  • How the pharmaceutical can regain public belief and resuscitate its image

Our knowing of human overall healthiness and ailment grows day-by-day; in spite of the fact that, changing technological know-how into drugs is more and more difficult. interpreting Devalued and Distrusted, you are going to not just achieve a better appreciation of these demanding situations, but in addition the function that the pharmaceutical at present performs and will play in fixing these challenges.

Get to understand the writer: Read an interview with John LaMattina or watch a video on ChemistryViews!

Interview: John LaMattina: 30 Years in Pharma

Video: Can the Pharmaceutical Restory its damaged Image?

Chapter 1 The 4 secrets and techniques the Drug businesses don't need You to grasp (pages 4–24):
Chapter 2 What has occurred to R&D productiveness? (pages 25–48):
Chapter three Key healing parts for bettering well-being (pages 49–70):
Chapter four enhancing R&D Output (pages 71–95):
Chapter five Restoring Pharma's photo (pages 96–108):
Chapter 6 ultimate concepts (pages 109–114):

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Additional resources for Devalued and Distrusted: Can the Pharmaceutical Industry Restore its Broken Image?

Sample text

12 If size is detrimental to an innovative research culture, mergers between large companies should make things worse—and they do. They have a strong negative personal impact on researchers and, consequently, the innovative research environment. For example, the merger of Bristol Myers with Squibb in 1989, which I witnessed, was a scene of power grabs and disintegrating morale. Researchers who could get a good offer left the company, and the positions of those who remained were often decided by favouritism rather than talent.

7 These two trends may be related. Smaller biotech companies and particularly start-up companies look to Big Pharma for support of new drug programs, especially as they enter more expensive clinical trials. As Big Pharma R&D budgets shrink, there is less money to invest both internally and externally. Thus, over the past 15 years, private sector R&D has been shrinking predominately in researchers but more recently in dollars invested. This is now occurring across the entire R&D health-care sector.

As a result, no venture capital firm will now finance a new effort to develop a drug for the obesity epidemic. Freund is not alone in these views. The CEO of the French pharmaceutical company Sanofi, Chris Viehbacher, echoed these same sentiments. 19 His concern is that companies cannot predict how the FDA will weigh the risk–benefit for drugs to treat diabetes and obesity. The result is that companies are shying away from R&D in this area. In reading this, one would think that the FDA is way too conservative in evaluating drugs, particularly in treating chronic diseases like obesity and diabetes that affect millions of Americans.

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