By Anatoliy I. Yashin, Eric Stallard, Kenneth C. Land (auth.)
This quantity is a severe exposition of the knowledge and analyses from an entire decade of rigorous examine into how age-related alterations on the person point, besides different elements, give a contribution to morbidity, incapacity and mortality dangers on the broader inhabitants point. After summarizing the nation of our wisdom within the box, person chapters supply enlightening dialogue on a number of key issues similar to age trajectory research in pick out and basic populations, incidence/age styles of significant continual health problems, and indices of cumulative deficits and their use in characterizing and realizing the distinct houses of person aging.
The publication gains complete statistical analyses of specific longitudinal facts units together with the original source of the Framingham middle examine, with its greater than 60 years of follow-up. Culminating in penetrating conclusions concerning the insights received from the paintings concerned, this ebook provides a lot to our figuring out of the hyperlinks among getting older and human health.
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Additional resources for Biodemography of Aging: Determinants of Healthy Life Span and Longevity
After age 70, the decline accelerates. The values of ventricular rate (VR) for males first increases, reaches a maximum around age 50 and then declines. For females, the average VR increases until age 45, and then shows a slight tendency to decline between ages 45 and 60. After age 60, it declines at a faster rate. Except for blood glucose, all average age trajectories of physiological indices differ between males and females. Statistical analysis confirms the significance of these differences.
18 1 Introduction: The Biodemography of Complex Relationships Among Aging. . Yashin, A. , Arbeev, K. , & Ukraintseva, S. V. (2008). Model of hidden heterogeneity in longitudinal data. Theoretical Population Biology, 73(1), 1–10. Yashin, A. , Ukraintseva, S. , Akushevich, I. , Arbeev, K. , & Akushevich, L. (2009). Trade-off between cancer and aging: What role do other diseases play? Evidence from experimental and human population studies. Mechanisms of Ageing and Development, 130(1–2), 98–104. Yashin, A.
Arbeeva, L. , Ukraintseva, S. V. (2014). Genetic structures of population cohorts change with increasing age: Implications for genetic analyses of human aging and life span. Current Gerontology and Geriatrics Research. 1(4), pii: 1020. PubMed PMID: 25893220; PubMed Central PMCID: PMC4398390. Yashin, A. , Arbeeva, L. , Arbeev. K. , Kulminski, A. , Ukraintseva, S. V. (2015) Genetics of aging, health, and survival: dynamic regulation of human longevity related traits. Frontiers in Genetics, 6(April 13), 122.